Integrity of Renal Function of Guinea Pigs Treated with Aqueous Root Extract of Telfairia Occidentalis

Adeeyo A.O[1a], Yusuf U.A[2a], Dare B.J[2b], Adenowo T.k[3a], Afolabi K.O[3b]
Page No. 102-105

The study investigated the effects of the aqueous root extract of Telfairia occidentalis on renal
functions by examine Serum Urea, Serum Creatinine and Serum Electrolytes of Guinea pigs . A total
of 10 Guinea pigs were randomly selected into two (2) groups A and B which were treated with 1ml
of distilled water and 200 mg/kg of Telfairia occidentalis for period of Six (6) weeks of experiment
respectively. Animals were sacrificed by cervical dislocation after the last administration and Blood
sample was collected for Serum creatinine concentrations, Serum Electrolytes and Serum urea
examination. Results obtained revealed an insignificant changes in the renal function as indicated
by the observed parameters.
Keywords : Renal function, Guinea pigs, Telfairia occidentalis, Antinutrient